"Ask Me Anything:10 Responses To Your Questions About ADHD Medication Pregnancy
ADHD Medication During Pregnancy and Breastfeeding
The decision to stop or continue ADHD medication during pregnancy and nursing is a difficult decision for women suffering from the condition. There is a lack of information about how long-term exposure to these drugs can affect the fetus.
A study recently published in Molecular Psychiatry shows that children exposed to ADHD medication during the uterus do not develop neurological developmental disorders such as hearing loss or impaired vision, febrile seizures, or IQ impairment. The authors acknowledge that more high-quality studies are needed.
Risk/Benefit Analysis
Pregnant women who use ADHD medications need to balance the benefits of taking them against the potential risks to the foetus. Doctors don't have enough data to give clear advice however they can provide information on the risks and benefits to assist pregnant women to make an informed decision.
A study published in Molecular Psychiatry concluded that women who took ADHD medication during early pregnancy did not have a greater risk of fetal malformations, or structural birth defects. The researchers used a large population-based case-control study to evaluate the incidence of major structural birth defects in babies born to mothers who had taken stimulants during the early stages of pregnancy, as well as those who had not. Clinical geneticists and pediatric cardiologists looked over the cases to ensure correct classification of the cases and to reduce the possibility of bias.
The study of the researchers was not without limitations. The researchers were unable, in the first place to differentiate the effects caused by the medication from the disorder. This limitation makes it difficult for researchers to determine whether the small associations observed among the groups exposed were due to the use of medications or confounded by comorbidities. Researchers also did not study long-term outcomes for offspring.
The study showed that infants whose mother took ADHD medication during pregnancy had a slightly higher chance of being admitted to the neonatal care unit (NICU) as compared to mothers who did not use any medication during pregnancy or discontinued taking their medication prior to or during pregnancy. The reason for this was central nervous system disorders. The higher risk of admission was not affected by the stimulant medication used during pregnancy.
Women who were taking stimulant ADHD medications during pregnancy also had a higher chance of having to have an emergency caesarean section or having the baby was not scoring well on the Apgar scale (less than 7). These increases appear to be unrelated to the type of medication taken during pregnancy.
The research suggests that the low risk associated with the use of ADHD medications during early pregnancy could be offset by the greater benefits for both mother and child of continued treatment for the woman's disorder. Physicians should discuss this with their patients and, if they are able, assist them in developing strategies to improve their coping abilities which can reduce the impact of her disorder on her daily life and relationships.
Medication Interactions
Many doctors are confronted with the dilemma of whether to keep treatment or stop as more women are diagnosed with ADHD. Most of the time, these decisions are made without clear and authoritative evidence in either case, which means that doctors have to weigh their experience, the experiences of other doctors, and what research suggests about the subject as well as their own best judgment for each patient.
Particularly, the issue of potential risks to the baby can be a challenge. Many studies on this subject are based on observations rather than controlled research, and their findings are often contradictory. Furthermore, most studies restrict their analysis to live births, which can underestimate severe teratogenic effects that cause abortion or termination of the pregnancy. The study discussed in this journal club addresses these limitations by looking at data from both live and deceased births.
Conclusion Some studies have shown an association between ADHD medications and certain birth defects however, other studies haven't shown such a relationship. Most studies show that there is a neutral, or somewhat negative, effect. In every case it is imperative to conduct a thorough analysis of the risks and benefits must be performed.
For many women with ADHD who suffer from ADHD, the decision to stop medication is difficult, if not impossible. In a recent article published in the Archives of Women's Mental Health by psychologist Jennifer Russell, she notes that stopping ADHD medications during pregnancy can increase depression and feelings of being isolated. The loss of medication can affect the ability to drive safely and perform work-related tasks, which are crucial aspects of daily life for those suffering from ADHD.
She recommends women who are uncertain about whether to continue or stop taking medication because of their pregnancy consider informing family members, friends, and coworkers on the condition, its effects on daily life, and the advantages of staying on the current treatment plan. Educating them can also make the woman feel more comfortable as she struggles with her decision. It is also worth noting that certain drugs can pass through the placenta, therefore, if a patient decides to stop taking her ADHD medication during pregnancy and breastfeeding, she must be aware that traces of the drug could be transferred to the infant.
Birth Defects Risk
As the use of ADHD drugs to treat symptoms of attention deficit hyperactivity disorder (ADHD) grows there are concerns over the impact that these medications could have on fetuses. Recent research published in the journal Molecular Psychiatry has added to the body of knowledge regarding this issue. Utilizing two huge data sets researchers were able analyze more than 4.3 million pregnancies to determine whether stimulant medications increased the risk of birth defects. Researchers discovered that although the risk overall is low, first-trimester ADHD medication use was associated with slightly higher risk of certain heart defects, like ventriculoseptal defect.
The authors of the study didn't discover any connection between early medication usage and other congenital anomalies like facial deformities, or club feet. The results are in line with previous studies that have shown a small, but significant increase in the number of cardiac malformations among women who started taking ADHD medication prior to the time of pregnancy. The risk was higher during the latter part of pregnancy, when a lot of women are forced to stop taking their medication.
Women who took ADHD medication during the first trimester were more likely to require a caesarean birth, have a low Apgar after birth and had a baby that required help breathing after birth. The researchers of the study could not eliminate selection bias because they limited their study to women who did not have any other medical conditions that could have contributed to the findings.
medication for adhd uk hope that their research will inform physicians when they meet pregnant women. The researchers suggest that, while discussing risks and benefits are important, the choice regarding whether or not to stop medication should be in light of the severity of each woman's ADHD symptoms and her needs.
The authors also advise that, while stopping the medication is an alternative, it is not a recommended practice because of the high rate of depression and other mental health issues in women who are pregnant or who are recently postpartum. Additionally, the research suggests that women who decide to stop their medications are more likely to experience a difficult time adjusting to life without them following the birth of their baby.

Nursing
It can be overwhelming becoming a mother. Women who suffer from ADHD are often faced with a number of difficulties when they have to manage their symptoms, go to doctor appointments, prepare for the birth of a baby and adjust to a new routine. Many women choose to continue taking their ADHD medication during pregnancy.
The risk to breastfeeding infant is not too high since the majority of stimulant medications is absorbed through breast milk at a low level. The rate of exposure to medication can vary depending upon the dosage, frequency of administration and the time of day. In addition, different medications are introduced into the baby's system via the gastrointestinal tract, or through breast milk. The impact of these medications on the health of a newborn isn't completely comprehended.
Due to the absence of research, some physicians may be inclined to discontinue stimulant medication during the course of pregnancy. This is a difficult decision for the patient, who must balance the benefit of continuing her medication against the potential risks to the fetus. In the meantime, until more information is available, doctors should ask all pregnant patients about their experience with ADHD and whether they plan or are taking to take medication during the perinatal period.
Numerous studies have proven that women can continue to take their ADHD medication in a safe manner during pregnancy and while breast-feeding. In response, a growing number of patients are opting to continue their medication. They have discovered, in consultation with their doctors, that the benefits of continuing their current medication far outweigh any possible risks.
Women who suffer from ADHD who are planning to nurse should seek advice from an expert psychiatrist prior to becoming pregnant. They should discuss the medication they are taking with their physician, and the pros and cons of continuing treatment. This includes non-pharmacological methods. Psychoeducation should also be provided to help women with ADHD understand their symptoms and the underlying disorder and learn about treatments and to reinforce existing strategies for coping. This should be a multidisciplinary approach including obstetricians, GPs, and psychiatrists. The pregnancy counselling should consist of the discussion of a treatment plan for both the mother and child, monitoring for signs of deterioration and, if necessary, adjustments to the medication regimen.